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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T22126 | Org 25543 hydrochloride | GlyT | |
Org 25543 hydrochloride is a potent and selective glycine transporter type 2 (GlyT2) inhibitor (IC50 = 16 nM for hGlyT2). Displays no activity at GlyT1 or 56 other common biological targets (≥ 100 μM), in a glycine uptak... | |||
T50082 | Org 25543 | Chloride channel | |
Org 25543 is the development of an N-Acyl amino acid that selectively inhibits the glycine transporter 2 to produce analgesia in a rat model of chronic pain. |